Wayne Rooney has not travelled with Manchester United for their Europa League tie with Anderlecht.
United boss Jose Mourinho has taken a 19-man squad to Brussels for the first leg of the quarter-final tie.
Rooney has been out of action with problems with both ankles, his last appearance coming as a late sub in a 0-0 draw at home to West Brom on April 1.
The United skipper, who has missed six of their last seven games, trained with the rear of the squad at the AON Training Complex today but was assessed afterwards and not deemed fit enough to travel.
Keeper David De Gea , who missed Sunday’s 3-0 win at Sunderland with a slight injury problem, has travelled but No.2 Sergio Romero is set to keep his place.
“He’s not happy with his condition, he’s trying to work with the team, which he does, but he’s not confident, not happy.
“He has a bad feeling with his ankle and is not ready to play. Let’s see for the weekend or the next game.
“We don’t have many players fit but for tomorrow? No.
Mourinho also discussed the Dortmund bus attack, which saw their Champions League clash with Monaco postponed.
“I try not to think much about it, I try to focus on our job and focus on what we are here t do, which is to play
“This is a quarter-final, we have to be focused on that and that is what we try to do. Obviously we have solidarity with what happened yesterday, with the people that were scared.
“But we have to trust the people who are working for our security, we have to believe the match tomorrow will be what people will want it to be, which is a very good game. So I repeat I just try to focus on the football.”
Confirmed United squad members
David de Gea