The defender is taking inspiration from playing in the Celtic team which stunned Lionel Messi and Barcelona with a 2-1 Champions League win in Glasgow five years ago.
And with an “Old Firm style” atmosphere expected at Hampden Park this weekend, Mulgrew is convinced Scotland can pull off a similar upset against Gareth Southgate’s men.
He said: “That night against Barcelona was huge for us. Nobody gave us a chance, but we pulled off a victory. I really hope we can do the same on Saturday.
“I think every player goes into every game believing they can get something. That night there must have been belief among us to get something or else we wouldn’t have achieved it.
“The likes of Harry Kane and Lionel Messi are always in your head, because of how good they are. But I think it maybe sharpens you up a bit and maybe sharpens your senses to realise how good these players are and all of a sudden you need to stop them.
“They are difficult nights. Trust me, they’re not easy. But we’ll all be giving everything we can to get something from the game.”
Kane is available to England for the first time since September, having missed their October, November and March internationals with two different ankle injuries.
The Tottenham striker has secured back-to-back Premier League Golden Boots, but Blackburn’s Mulgrew says Scotland — beaten 3-0 at Wembley in November’s reverse fixture — can’t concentrate on bottling up Kane, as England have weapons elsewhere.
He added: “You stop Harry, but then who else is there? There’s Sterling, there’s so many of them. You can’t just pick out one to stop. You stop one, then someone else will step up.. like Jermain Defoe.
“It’s a team of world-class players and we’ve got to be prepared and ready for it.
“We know all their possibilities, what they can do and what they can’t do. We need to turn up on the night and deliver.”
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