Sanchez is being strongly linked with a move away from Emirates Stadium as uncertainty continues to surround the long-term future of Wenger.
The Arsenal boss has still not put pen to paper on a new contract and is refusing to give anything away when he is constantly asked about his position with the club.
The future of Sanchez is also a major talking point among Arsenal fans and there is a worry that he could follow in the footsteps of Van Persie and demand a move at the end of the season.
But Wenger has been quick to defend his star forward after comparisons were made between his situation and when RVP was dramatically allowed to join Manchester United back in the summer of 2012.
Wenger, speaking in The Sun, said: “I let Van Persie go in the last year of his contract because he was 29, going on 30 and he was signing a long-term contract.
“That is not the case with Alexis. I personally think he will sign and stay here.”
The Gunners boss is determined to see the Chile star remain at the north London club and says he will do everything in his power to ensure that happens – even if he walks away during the summer.
Wenger added: “Even if he doesn’t sign a new deal, I will make him stay? Yes.”
Van Persie left the north London club in bad terms following a difference of opinion with Wenger.
- Pockets of empty seats at the Etihad as fans held0:35
- 2012: Robin van Persie speaks after joining Manch0:39
- Jose Mourinho pays tribute to Inter chairman Mass0:58
- Sean Dyche says Joey Barton ban is ‘harsh’5:04
- Notts County steward caught on camera kicking fan1:41
- Friend secretly gets Spurs logo tattooed on his A0:30
- Neymar suffers massive keepy-up fail0:35
- Insane moves from the Chalobah brothers following0:40
Wenger reacts to Alexis Sanchez’s controversial yellow card
The Dutch forward felt Arsenal lacked the ambition to challenge for major silverware and was determined to win major silverware with another big club.
Van Persie said at the time: “I personally have had a great season but my goal has been to win trophies with the team and to bring the club back to its glory days.
“Out of my huge respect for Mr. Wenger, the players and the fans I don’t want to go into any details, but unfortunately in this meeting it has again become clear to me that we in many aspects disagree on the way Arsenal FC should move forward.”
The Arsenal supporters will now be praying that Sanchez does not go down a similar route and will pledge his long-term future to the club at the end of the season.